The CD8a antibody (PE-Texas Red) from MyBioSource.com is a Rat Monoclonal antibody to CD8, and CD8A. This antibody recognizes Human antigen. The CD8a antibody (PE-Texas Red) has been validated for the following applications: Flow Cytometry, and Immunohistochemistry.
Description
Rat monoclonal CD8a antibody (PE-Texas Red)
CD8a (Cluster of Differentiation 8a), is a human gene. The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Two alternative transcripts encoding distinct isoforms, one membrane associated and one secreted, have been identified